Journal: Science Advances
Authors: C. M. Proctor and G. G. Malliaras et al.
Affiliation: The University of Cambridge (UK)
Publication date: 2018.08.29
Summarized by Inyeol Yun
v. Neural probes incorporation an ion pump for on-demand drug delivery and electrodes for recording local neural activity. (Fig. 1)
v. Seizure-like events (SLE) were induced by local injection of 4-aminopryridine (4AP)
v. γ-aminobutryic acid (GABA) inhibit neural activity.
v. Gold electrode: ion pump source electrode, PEDOT:PSS electrode : recording electrophysiological activity (Fig. 2)
v. Ion transfer efficiency: ~10-3 nmol of GABA transported in few seconds (Fig. 3)
v. Seizure control (Fig. 4)