Flexible Piezoelectric Devices for Gastrointestinal Motility Sensing

Journal: Nature Biomedical Engineering

Author: C. Dagdeviren and G. Traverso et al.

Affiliation: Massachusetts Institute of Technology, Cambridge, United States

Publication date: 2017.10

Summarized by Inyeol Yun

 

– Piezoelectric gastrointestinal motility sensor (Fig. 1)

v. 12 groups in series, 10 groups in parallel. (Fig. 2)

v. Sensing principle: piezoelectric material (Fig. 3)

fig1

Fig. 1

Fig. 2

fig3.png

Fig. 3

 

– Biocompatibility

v. Live/dead cytotoxicity analysis of HT-29-MTX-E12, HeLa and C2BBe1 cells incubated with neutralized simulated gastric fluid for three days.

v. Cells treated with 70% ethanol were used as a negative control.

v. Cells treated with neutralized gastric fluid that had not been in contact with the microchips were used as a positive control

v. Green indicates viable cells and red indicates dead cells. (Fig. 4)

fig4.png

Fig. 4

 

– Result

v. Voltage output for a flouting and glued PZT GI-S in a balloon with 200 ml water infusion (Fig. 5)

v. In vivo evaluation in Yorkshire swine model (Fig. 6)

fig5

Fig. 5

fig6.png

Fig. 6

 

– Reference

v. http://blog.naver.com/kt9411/150165849100 (2017-11-21)

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