Top Down Fabrication Meets Bottom-up Synthesis for Nanoelectronic Barcoding of Micro Particles

Journal: Lab on a chip

Publication date: 2017. 06

Summarized by Jinpyeo Jeung


– Nanoelectrically barcoded micro particles (Fig. 1)

v. Could be used in biomarker based diagnostics

v. Allows miniaturization of the readout instrument thus suitable for wearable device

v. Structure similar to Janus microparticles (JPs)

v. Polystyrene bead (3μm diameter), gold (20nm), Aluminium oxide (5nm, 20nm)

v. Due to difference in capacitance of bead, shows different frequency response (Fig. 2)


Fig. 1


Fig. 2


– Fabrication (Fig. 3)

v. Polystyrene microsphere self assembled onto a glass substrate using drop-casting

v. Wafer heated to evaporate liquid

v. Using electron beam evaporation, deposited gold layer

v. Using ALD, deposited an insulative layer

v. Particles lifted off from the film using ultrasonification


Fig. 3


– Result (Fig. 4)

v. 4 different bead could be distinguished by frequency response data

v. successful barcoding of micro particles


Fig. 4